Publications

119) “Organocatalytic activation of hydrogen peroxide: towards green and sustainable oxidations” E. T. Poursaitidis, P. L. Gkizis, I. Triandafillidi and C. G. Kokotos*, Chem. Sci., 2024, 14, doi: 10.1039/D3SC05618J. 

 

118) “Nitroarenes: The rediscovery of their photochemistry opens new avenues in organic synthesis” P. L. Gkizis, I. Triandafillidi, and C. G. Kokotos*, Chem, 2023, 9, 3401-3414.

 

 

117) “Organocatalytic Friedel-Crafts Arylation of Aldehydes with Indoles utilizing N-Heterocyclic Iod(az)olium Salts as the Halogen-Bonding Catalyst” E. M. Galathri, T. Kuczmera, B. J. Nachtsheim* and C. G. Kokotos*, Green Chem., 2024, 26, doi: 10.1039/D3GC03687A.

 

116) “UVA-Light Promoted Catalyst-Free Photochemical Aerobic Oxidation of Boronic Acids” P. L. Gkizis, C. T. Constantinou and C. G. Kokotos*, Eur. J. Org. Chem., 2023, e202300898.

 

115) “3H‐Phenothiazin‐3‐one: A New Photocatalyst for the Aerobic Photochemical Oxidation of Sulfides to Sulfoxides” C. K. Spyropoulou, E. Skolia, D. F. Flesariu, G. A. Zissimou, P. L. Gkizis, I. Triandafillidi, M. Athanasiou, G. Itskos, P. A. Koutentis and C. G. Kokotos*, Adv. Synth. Catal., 2023, 365, 2643-2650. (citations: 0) (IF: 5.4)

 

114) “Photochemical Amino-Chlorination of Alkenes Without the Use of an External Catalyst” C. T. Constantinou, P. L. Gkizis, O. T. G. Lagopanagiotopoulou, E. Skolia, N. F. Nikitas, I. Triandafillidi, C. G. Kokotos, Chem. Eur. J. 2023, e202301268.

 

 

113) “Photochemical Aerobic Upcycling of Polystyrene Plastics to Commodity Chemicals Using Anthraquinone as the Photocatalyst” N. F. Nikitas, E. Skolia, P. L. Gkizis, I. Triandafillidi, C. G. Kokotos* Green Chem., 2023 DOI: 10.1039/d3gc00986f

112) An Efficient Light-Mediated Protocol for the Direct Amide Bond Formation via a Novel Carboxylic Acid Photoactivation Mode by Pyridine-CBr4” O. G. MountaneaD. Psathopoulou, C. Mantzourani, M. G. KokotouE. A. RoutsiD. Tzeli, C. G. Kokotos, G. Kokotos, Chem. Eur. J., 2023, e202300556.

 

111) Anthraquinone-catalyzed Photooxidation of Boronic Acids in a Bio-based Solvent (2-Me-THF) P. L. Gkizis, S. K. Serviou, A. Balaskas, C. T. Constantinou, I. Triandafillidi, C. G. Kokotos*, Synlett, 2023

 

110) “Visible-Light-Promoted Reaction of N-Hydroxyphthalimide Esters with Vinyl Boronic Pinacol Ester” P. L. Gkizis, I. Triandafillidi, N. A. Stini, C. S. Batsika, C. G. Kokotos*, Eur. J. Org. Chem., 2023, 26, e2023001.

 

 

 

109) “A Photochemical Protocol for the Synthesis of Weinreb and Morpholine Amides from Carboxylic Acids” O. G. Mountanea, C. Mantzourani, M. G. Kokotou, C. G. Kokotos*, G. Kokotos, Eur. J. Org. Chem., 2023, e202300008.

 

 

 

 

108) ''Sunlight- or UVA-Light-Mediated Synthesis of Hydroxamic Acids from Carboxylic Acids” Olga G. Mountanea, C. Mantzourani, Maroula G. Kokotou, C. G. Kokotos*, Eur.J. Org.Chem., 2023, 26, e20230004.

 

 

107) “Photochemical upcycling of polystyrene plastics” E. Skolia, O. G. Mountanea and C. G. Kokotos*, Trends Chem., 2023, 5, 116-120.

 

106) “A General Metal-Free Protocol for the Visible-Light-Driven Protection of Carbonyls” L. Di Terlizzi, E. M. Galathri, S. Protti, C. G. Kokotos and M. Fagnoni*, ChemSusChem, 2023, 16, e202201998.

 

 

105) “Photochemical [2+2] Cycloaddition of Alkenes with Maleimides: Highlighting the Differences between N-Alkyl vs N-Aryl Maleimides” E. Skolia and C. G. Kokotos*, ACS Org Inorg Au, 2023, 3, 96-103.

 

104) “Light-accelerated “on-water” hydroacylation of dialkyl azodicarboxylates” N. A. Stini, E. T. Poursaitidis, N. F. Nikitas, M. Kartsinis, N. Spiliopoulou, P. Ananida-Dasenaki and C. G. Kokotos*, Org. Biomol. Chem., 2023, 21, 1284-1293.

 

103) “Friedel–Crafts arylation of aldehydes with indoles utilizing arylazo sulfones as the photoacid generator” E. M. Galathri, L. Di Terlizzi, M. Fagnoni, S. Protti and C. G. Kokotos*, Org. Biomol. Chem., 2023, 21, 365-369.

 

 

102) “Cyrene: A Bio-based Solvent for the Mizoroki-Heck Reaction of Aryl Iodides” N. A. Stini, P. L. Gkizis and C. G. Kokotos*, Org. Biomol. Chem., 2023, 21, 351-358.

 

101) “Photochemical Aerobic Upcycling of Polystyrene Plastics to Commodity Chemicals” N. F. Nikitas and C. G. Kokotos*, ChemRxiv, 2022, doi: 10.26434/chemrxiv-2022-l8p90.

 

 

100) “Cyrene: a Bio-based Novel and Sustainable Solvent for Organic Synthesis” N. A. Stini, P. L. Gkizis and C. G. Kokotos*, Green Chem., 2022, 24, 6435-6449.

 

 

99) “Light-promoted Oxidation of Aldehydes to Carboxylic Acids under Aerobic and Photocatalyst-free Conditions” C. S. Batsika, C. Koutsilieris, G. S. Koutoulogenis, M. G. Kokotou, C. G. Kokotos* and G. Kokotos*, Green Chem., 2022, 24, 6224-6231.

 

 

 

98) “A Sustainable Photochemical Aerobic Sulfide Oxidation: Access to Sulforaphane and Modafinil” E. Skolia, P. L. Gkizis and C. G. Kokotos*, Org. Biomol. Chem., 2022, 20, 5836-5844.

 

97) “Organocatalytic Synthesis of Thiiranes from Alkenes” A. Tsoukaki, E. Skolia, I. Triandafillidi* and C. G. Kokotos*, Eur. J. Org. Chem., 2022, e202200463. Hot Topic Organocatalysis, Highlighted at ChemistryViews:

 

96) “Photochemical Aerobic Oxidation of Sulfides to Sulfoxides: The Crucial Role of Wavelength Irradiation” E. Skolia, P. L. Gkizis, N. F. Nikitas and C. G. Kokotos*, Green Chem, 2022, 24, 4108-4118.

 

 

 

95) “Aerobic Photocatalysis: Oxidation of Sulfides to Sulfoxides” E. Skolia, P. L. Gkizis and C. G. Kokotos*, ChemPlusChem, 2022, 87, e202200008.

 

 

 

94) “A Unified Mechanism for the PhCOCOOH-mediated Photochemical Reactions: Revisiting its Action and Comparison to Known Photoinitiators” N. Spiliopoulou, P. L. Gkizis, I. Triandafillidi, N. F. Nikitas, C. S. Batsika, A. Bisticha and C. G. Kokotos*, Chem. Eur. J., 2022, 28, e202200023.

 

 

 

93) “Hexafluoroisopropanol-promoted or Brψnsted Acid-mediated Photochemical [2+2] Cycloadditions of Alkynes ChemSusChem 2022, 15, e2021024.

92) “Photochemical C–H Acetalization of O-Heterocycles utilizing Phenylglyoxylic Acid as the Photoinitiator” G. S. Koutoulogenis, N. Spiliopoulou and C. G. Kokotos*, PhotoChem. PhotoBiol. Sci., 2022, 21, 687-694. Invited Contribution for Special Issue for Prof. Albini

 

 

 

91) “Aldehyde-Catalyzed Epoxidation of Unactivated Alkenes with Aqueous Hydrogen Peroxide” I. Triandafillidi, M. G. Kokotou, D. Lotter, C. Sparr* and C. G. Kokotos*, Chem. Sci., 2021, 12, 10191-10196. 

 

 

90) “Saturated Oxo Fatty Acids (SOFAs): A Previously Unrecognized Class of Endogenous Bioactive Lipids Exhibiting a Cell Growth Inhibitory Activity” C. S. Batsika, C. Mantzourani, D. Gkikas, M. G. Kokotou, O. G Mountanea, C. G. Kokotos P. K. Politis and G. Kokotos*, J. Med. Chem., 2021, 64, 5654-5666.

 

 

89) “Photochemical Activation of Aromatic Aldehydes: Synthesis of Amides, Hydroxamic Acids and Esters” N. F. Nikitas, M. K. Apostolopoulou, E. Skolia, A. Tsoukaki and C. G. Kokotos*, Chem. Eur. J., 2021, 27, 7915-7922.

 

 

88) “Thioxanthone: A Powerful Photocatalyst for Organic Reactions” N. F. Nikitas, P. L. Gkizis and C. G. Kokotos*, Org. Biomol. Chem., 2021, 19, 5237-5253.

 

87) “Organocatalytic, Organic Oxidant Promoted, Enamine CH Oxidation/Cyclopropanation Reaction” Z. Džambaski, A. M. Bondžić, I. Triandafillidi, C. G. Kokotos and B. P. Bondžić*, Adv. Synth. Catal., 2021, 363, 4002–4008.

 

 

86) “Photochemical Metal-free Aerobic Oxidation of Thiols to Disulfides” N. Spiliopoulou and C. G. Kokotos*, Green Chem., 2021, 23, 546-551.

 

 

85) “Metal‐free Photochemical Atom Transfer Radical Addition (ATRA) of BrCCl3 to Alkenes” N. F. Nikitas, E. Voutyritsa, P. L. Gkizis and C. G. Kokotos*, Eur. J. Org. Chem., 2021, 96-101. Invited Contribution for Special Issue: YourJOC Talents

 

 

84) “Photochemical Synthesis of Benzimidazoles from Diamines and Aldehydes” E. Skolia, M. K. Apostolopoulou, N. F. Nikitas and C. G. Kokotos*, Eur. J. Org. Chem., 2021, 422-428.

 

 

83) “Photochemical Reaction of N,N‐Dimethylanilines with N‐Substituted Maleimides Utilizing Benzaldehyde as the Photoinitiator” N. F. Nikitas, M. A. Theodoropoulou and C. G. Kokotos*, Eur. J. Org. Chem., 2021, 1168-1173. Invited Contribution for Special Issue: Hot Topic: Organocatalysis

 

82) “Phenylglyoxylic Acid: An Efficient Initiator for the Photochemical Hydrogen Atom Transfer (HAT) C‐H Functionalization of Heterocycles” G. N. Papadopoulos, M. G. Kokotou, N. Spiliopoulou, N. F. Nikitas, E. Voutyritsa, D. I. Tzaras, N. Kaplaneris and C. G. Kokotos*, ChemSusChem, 2020, 13, 5934-5944.

 

 

81) “Photochemical Functionalization of Heterocycles with EBX Reagents; C‐H Alkynylation versus Deconstructive Ring Cleavage” E. Voutyritsa, M. Garreau, M. G. Kokotou, I. Triandafillidi, J. Waser* and C. G. Kokotos*, Chem. Eur. J., 2020, 26, 14453-14460.

 

 

80) “Green Metal-Free Photochemical Hydroacylation of Unactivated Olefins” E. Voutyritsa and C. G. Kokotos*, Angew. Chem. Int. Ed., 2020, 59, 1735-1741.

 

79) “Photochemical Synthesis of Acetals utilizing Schreiner's Thiourea as the Catalyst” N. Spiliopoulou, N. F. Nikitas and C. G. Kokotos*, Green Chem., 2020, 22, 3539-3545.

78) “Photochemical oxidation of benzylic primary and secondary alcohols utilizing air as the oxidant” N. F. Nikitas, D. I. Tzaras, I. Triandafillidi and C. G. Kokotos*, Green Chem., 2020, 22, 471-477.

 

 

77) “Aldehydes as powerful initiators for photochemical transformations” M. A. Theodoropoulou, N. F. Nikitas and C. G. Kokotos*, Beilstein J. Org. Chem., 2020, 16, 833-857.

 

 

76) “Synthetic Approaches to Acyl Hydrazides and Their Use as Synthons in Organic Synthesis” N. Spiliopoulou, C. T. Constantinou, I. Triandafillidi* and C. G. Kokotos*, Synthesis, 2020, 22, 3219-3230.

 

 

 

75) “Recent advances in reactions promoted by amino acids and oligopeptides” I. Triandafillidi, E. Voutyritsa and C. G. Kokotos*, Phys. Sci. Rev., 2020, 5, doi.org/10.1515/psr-2018-0086.

 

 

74) “ Photochemical Hydroacylation of Michael Acceptors Utilizing an Aldehyde as Photoinitiator” I. K. Sideri, E. Voutyritsa and C. G. Kokotos*, ChemSusChem, 2019, 12, 4194-4201.

 

73) “ Synthesis of γ-Lactones Utilizing Ketoacids and Trimethylsulfoxonium Iodide” I. Triandafillidi, A. Savvidou and C. G. Kokotos*, Org. Lett., 2019, 21, 5533-5537.

 

72) “Synthesis of Benzofuran and Indole Derivatives Catalyzed by Palladium on Carbon” A. Savvidou, D. I. Tzaras, G. S. Koutoulogenis, A. Theodorou and C. G. Kokotos*, Eur. J. Org. Chem., 2019, 3890-3897.

 

 

71) “Photoorganocatalytic Synthesis of Acetals from Aldehydes” N. F. Nikitas, I. Triandafillidi and C. G. Kokotos*, Green Chem., 2019, 21, 669-674.

 

 

70) “Enantioselective Organocatalytic Enamine C-H Oxidation/Diels-Alder Reaction” Z. Dzambaski, D.-I. Tzaras, S. Lee, C. G. Kokotos and B. P. Bondzic*, Adv. Synth. Catal., 2019, 361, 1792-1797.

 

 

69) “Photocatalytic Atom Transfer Radical Addition to Olefins utilizing Novel Photocatalysts” E. Voutyritsa, I. Triandafillidi, N. V. Tzouras, N. F. Nikitas, E. K. Pefkianakis, G. C. Vougioukalakis and C. G. Kokotos*, Molecules, 2019, 24, 1644-1653.

 

68) “Photocatalytic Synthesis of γ-Lactones from Alkenes: High-Resolution Mass Spectrometry as a Tool to Study Photoredox Reactions” I. Triandafillidi, M. G. Kokotou and C. G. Kokotos*, Org. Lett., 2018, 20, 36-39.

 

 

 

67) “Organocatalytic Synthesis of Oxazolines and Dihydrooxazines from Allyl-Amides: Bypassing the Inherent Regioselectivity of the Cyclization” A. Theodorou, I. Triandafillidi and C. G. Kokotos*, Adv. Synth. Catal., 2018, 360, 951-957.

 

 

66) “Green Photo-Organocatalytic CH Activation of Aldehydes: Selective Hydroacylation of Electron-Deficient Alkenes” G. N. Papadopoulos, E. Voutyritsa, N. Kaplaneris and C. G. Kokotos*, Chem. Eur. J., 2018, 24, 1726-1731.

 

65) “Expanding the Scope of Photocatalysis: Atom Transfer Radical Addition of Bromoacetonitrile to Aliphatic Olefins” E. Voutyritsa, I. Triandafillidi and C. G. Kokotos*, ChemCatChem, 2018, 10, 2466-2470.

 

 

64) “Photoorganocatalysis, Small Organic Molecules and Light in the Service of Organic Synthesis: the Awakening of a Sleeping Giant” I. K. Sideri, E. Voutyritsa and C. G. Kokotos*, Org. Biomol. Chem., 2018, 16, 4596-4614. Invited Review.

63) “Combining Οrganocatalysis with Photoorganocatalysis: Photocatalytic Hydroacylation of Asymmetric Organocatalytic Michael Addition Products” A. Schiza, N. Spiliopoulou, A. Shahu and C. G. Kokotos*, New J. Chem., 2018, 42, 18844-18849.

 

62) “Proline Dipeptides Containing Fluorine Moieties as Organocatalysts for the Asymmetric Aldol Reaction” A. Ahmetlli, N. Spiliopoulou, A. Magi-Oikonomopoulou, D.-T. Gerokonstantis, P. Moutevelis-Minakakis* and C. G. Kokotos*, Tetrahedron, 2018, 74, 5987-5995.

 

61) “Green Organocatalytic Oxidative Methods using Activated Ketones” I. Triandafillidi, D. I. Tzaras, and C. G. Kokotos*, ChemCatChem, 2018, 10, 2521-2535.

 

 

 

60) “Combining Prolinamides with 2-Pyrrolidinone: Novel Organocatalysts for the Asymmetric Aldol Reaction” I. Vlasserou, M. Sfetsa, D. T. Gerokonstantis, C. G. Kokotos* and P. Moutevelis-Minakakis*, Tetrahedron, 2018, 74, 2338-2349.

 

 

59) “Photoorganocatalytic Atom Transfer Radical Addition of Bromoacetonitrile to Aliphatic Olefins” E. Voutyritsa, N. F. Nikitas, M. K. Apostolopoulou, A. D. D. Gerogiannopoulou and C. G. Kokotos*, Synthesis, 2018, 50, 3395-3401. Invited Contribution for Special Issue: Photoredox Methods and their Strategic Applications in Synthesis

 

58) “Green Photoorganocatalytic Synthesis of Phenols from Arylboronic Acids” I. K. Sideri, E. Voutyritsa and C. G. Kokotos*, Synlett, 2018, 29, 1324-1328. Invited Contribution for Special Issue: 9th EuCheMS Organic Division Young Investigator Workshop

 

57) “Organocatalytic Synthesis of Lactones by the Oxidation of Alkenoic Acids” I. Triandafillidi, M. Raftopoulou, A. Savvidou, and C. G. Kokotos*, ChemCatChem, 2017, 9, 4120-4124.

 

 

56) “Photoorganocatalytic Synthesis of Lactones via a Selective C–H Activation–alkylation of Alcohols” N. Kaplaneris, A. Bisticha, G. N. Papadopoulos, D. Limnios and C. G. Kokotos*, Green Chem., 2017, 19, 4451-4456.

55) “Visible-Light-Mediated Catalytic Hydroacylation of Dialkyl Azodicarboxylates by Graphite Flakes” G. S. Koutoulogenis, M. G. Kokotou, E. Voutyritsa, D. Limnios, C. G. Kokotos*, Org Lett., 2017, 19, 1760-1763.

 

 

54) “Organocatalytic Oxidation of Substituted Anilines to Azoxybenzenes and Nitro Compounds: Mechanistic Studies Excluding the Involvement of a Dioxirane Intermediate” E. Voutyritsa, A. Theodorou, M. G. Kokotou and C. G. Kokotos*, Green Chem., 2017, 1291-1298. 2017 Green Chemistry Hot

 

 

 

53) “Green Organocatalytic Synthesis of Indolines and Pyrrolidines from Alkenes” A. Theodorou and C. G. Kokotos*, Adv. Synth. Catal., 2017, 359, 1577-1581.

 

 

52) “Green Organocatalytic Synthesis of Isoxazolines via a One-Pot Oxidation of Allyloximes” I. Triandafillidi and C. G. Kokotos*, Org. Lett., 2017, 19, 106-109.

51) “Photoinitiated Thiol-Ene “Click” Reaction: An Organocatalytic Alternative” D. Limnios and C. G. Kokotos*, Adv. Synth. Catal., 2017, 359, 323-328.

 

50) “Organocatalytic Synthesis of Polysubstituted Tetrahydrofurans from Alkenes” A. Theodorou and C. G. Kokotos*, Green Chem., 2017, 19, 670-674.

 

49) “Green Organocatalytic Dihydroxylation of Alkenes” A. Theodorou, I. Triandafillidi and C. G. Kokotos*, Eur. J. Org. Chem., 2017, 11, 1502-1509.

 

 

 

48) “Green Organocatalytic Synthesis of Dihydrobenzofurans by Oxidation-Cyclization of Allylphenols” I. Triandafillidi, I. K. Sideri, D. I. Tzaras, N. Spiliopoulou and C. G. Kokotos*, Synthesis, 2017, 49, 4254-4260. Invited Contribution for Special Issue: Modern Strategies in Cyclization

 

47) “Green Organocatalytic Oxidation of Sulfides to Sulfoxides and Sulfones” E. Voutyritsa, I. Triandafillidi and C. G. Kokotos*, Synthesis, 2017, 49, 917-924.

 

 

46) “Enantioselective Organocatalytic Synthesis of 2-Oxopiperazines from Aldehydes: Identification of the Elusive Epoxy Lactone Intermediate” N. Kaplaneris, C. Spyropoulos, M. G. Kokotou and C. G. Kokotos*, Org. Lett., 2016, 18, 5800-5803.

 

 

45) “One-pot Amide Bond Formation from Aldehydes and Amines via a Photoorganocatalytic Activation of Aldehydes” G. N. Papadopoulos and C. G. Kokotos*, J. Org. Chem., 2016, 81, 7023-7028.

44) “Photoorganocatalytic One-pot Synthesis of Hydroxamic Acids from Aldehydes” G. N. Papadopoulos and C. G. Kokotos*, Chem. Eur. J., 2016, 22, 6964-6967.

 

 

43) “Green Organocatalytic α-Hydroxylation of Ketones” E. Voutyritsa, A. Theodorou and C. G. Kokotos*, Org. Biomol. Chem., 2016, 14, 5708-5713. Invited Article for the Special Thematic issue “New Talent in Organic and Medicinal Chemistry”.

 

 

42) “(Thio)urea-mediated Synthesis of Functionalized Six-membered Rings with Multiple Chiral Centers” G. Koutoulogenis, N. Kaplaneris and C. G. Kokotos*, Beilstein J. Org. Chem., 2016, 12, 462-495. Invited Article for the Special issue “Multifunctional Organocatalysis”.

 

 

 

41) “4-Fluoro and 4-Hydroxy Pyrrolidine-thioxotetrahydropyrimidinones: Organocatalysts for Green Asymmetric Transformations in Brine” N. Kaplaneris, G. Koutoulogenis, M. Raftopoulou and C. G. Kokotos*, J. Org. Chem., 2015, 80, 5464-6473.

 

40) tert-Butyl Esters of Peptides as Organocatalysts for the Asymmetric Aldol Reaction” A. Bisticha, I. Triandafillidi and C. G. Kokotos*, Tetrahedron: Asymmetry, 2015, 26, 102-108.

 

 

39) “One-pot Synthesis of O-Allylhydroxylamines through the Organocatalytic Oxidation of Tertiary Allylic Amines followed by a [2,3]-Meisenheimer Rearrangement” A. Theodorou, D. Limnios and C. G. Kokotos*, Chem. Eur. J., 2015, 21, 5238-5241.

 

 

38) tert-Butyl Ester or Benzylamide of the Dipeptide Pro-Gly as Organocatalysts for the Asymmetric Aldol Reaction” I. Triandafillidi, A. Bisticha, E. Voutyritsa, G. Galiatsatou and C. G. Kokotos*, Tetrahedron, 2015, 71, 932-940

 

 

37) “Conjugating Proline Derivatives onto Multi-walled Carbon Nanotubes: Preparation, Characterization and Catalytic Activity in Water” D. D. Chronopoulos, C. G. Kokotos, M. Tsakos, N. Karousis, G. Kokotos and N. Tagmatarchis, Mat. Lett., 2015, 157, 212-214.

 

36) “Functionalized Multi-walled Carbon Nanotubes in an Aldol Reactions” D. D. Chronopoulos, C. G. Kokotos, N. Karousis, G. Kokotos* and N. Tagmatarchis*, Nanoscale, 2015, 7, 2750-2757.

 

 

35) “Organocatalytic Oxidation Reactions” D. Limnios and C. G. Kokotos*, Current Organocatalysis, 2015, 2, 171-190.

 

 

34) “Fullerene-proline Hybrids: Synthesis, Characterization and Organocatalytic Properties in Aldol Reactions” D. D. Chronopoulos, M. Tsakos, N. Karousis, C. G. Kokotos* and N. Tagmatarchis*, Mat. Lett., 2014, 137, 343-346.

 

 

33) “Photoorganocatalytic Hydroacylation of Dialkyl Azodicarboxylates by utilizing Activated Ketones as Photocatalysts” G. N. Papadopoulos, D. Limnios and C. G. Kokotos*, Chem. Eur. J., 2014, 20, 13811-13814.

 

32) “2,2,2-Trifluoroacetophenone: An Organocatalyst for an Environmentally Friendly Epoxidation of Alkenes” D. Limnios and C. G. Kokotos*, J. Org. Chem., 2014, 79, 4270-4276.

31) “One-pot Synthesis of Ureas from Boc-Protected Amines” C. Spyropoulos and C. G. Kokotos*, J. Org. Chem., 2014, 79, 4477-4483.

 

30) “2,2,2-Trifluoroacetophenone as an Organocatalyst for the Oxidation of Tertiary Amines and Azines to N-Oxides” D. Limnios and C. G. Kokotos*, Chem. Eur. J., 2014, 20, 559-563.

 

29) tert-Butyl Esters of Tripeptides based on Pro-Phe as Organocatalysts for the Asymmetric Aldol Reaction in Aqueous or Organic Medium” A. Psarra, C. G. Kokotos* and P. Moutevelis-Minakakis*, Tetrahedron, 2014, 70, 608-615.

 

28) “Primary and Secondary Amine-(thio)ureas and Squaramides and their Applications in Asymmetric Organocatalysis” M. Tsakos and C. G. Kokotos*, Tetrahedron, 2013, 69, 10199-10222.

27) “Organocatalytic Oxidation of Organosilanes to Silanols” D. Limnios and C. G. Kokotos*, ACS Catalysis, 2013, 3, 2239-2243.

26) “β-tert-Butyl Aspartate as an Organocatalyst for the Asymmetric α-Amination of α,α-Disubstituted Aldehydes” A. Theodorou, G. N. Papadopoulos and C. G. Kokotos*, Tetrahedron, 2013, 69, 5438-5443.

 

 

25) “An Asymmetric Michael Addition of α,α-Disubstituted Aldehydes to Maleimides leading to a One-pot Enantioselective Synthesis of Lactones Catalyzed by Amino Acids” C. G. Kokotos*, Org. Lett., 2013, 15, 2406-2409.

 

 

24) “Microwave-Assisted Organocatalytic Cross-Aldol Condensation of Aldehydes” D. Limnios and C. G. Kokotos*, RSC Adv., 2013, 3, 4496-4499.

 

23) “Organocatalytic Asymmetric Domino Michael-Henry Reaction for the Synthesis of Substituted Bicyclo[3.2.1]octan-2-ones” M. Tsakos, M. R. J. Elsegood and C. G. Kokotos*, Chem. Commun., 2013, 49, 2219-2221.

 

 

22) “Novel Prolinamide-Ureas as Organocatalysts for the Asymmetric Aldol Reaction” P. Revelou, C. G. Kokotos* and P. Moutevelis-Minakakis*, Tetrahedron, 2012, 68, 8732-8738.

 

21) “Pyrrolidine-thioxotetrahydropyrimidinone as an Efficient Organocatalyst for the Enantioselective Michael Addition of Cyclic Ketones to Nitrodienes” M. Tsakos. M. Trifonidou and C. G. Kokotos*, Tetrahedron, 2012, 68, 8630-8635.

 

20) “A Tripeptide-like Prolinamide-Thiourea as an Aldol Reaction Catalyst” S. Fotaras, C. G. Kokotos and G. Kokotos, Org. Biomol. Chem., 2012, 10, 5613-5619. 

 

 

19) “Primary Amine-Thioureas with Improved Catalytic Properties for “Difficult” Michael Reactions. Efficient Organocatalytic Syntheses of (S)-, (R)-Baclofen and (S)-Phenibut” M. Tsakos, C. G. Kokotos and G. Kokotos, Adv. Synth. Catal., 2012, 354, 740-746.

 

 

 

18) “Enantioselective Organocatalytic α-Alkylation of Ketones Utilising SN-1 Type Reaction of Alcohols” M. Trifonidou and C. G. Kokotos*, Eur. J. Org. Chem., 2012, 1563-1568.

 

17) “Construction of Tertiary Alcohols Bearing Perfluoroalkyl Chains Catalyzed by Prolinamide-Thioureas” C. G. Kokotos*, J. Org. Chem., 2012, 77, 1131-1135.

 

 

16) “Organocatalytic “Difficult” Michael Reaction of Ketones with Nitrodienes Utilising Primary Amine-Thioureas Based on di-tert-Butyl Esters of Aspartic Acid” M. Tsakos and C. G. Kokotos*, Eur. J. Org. Chem., 2012, 576-580.

 

 

15) “Novel Pyrrolidine-thiohydantoins/thioxotetrahydropyrimidinones as Highly Effective Catalysts for the Asymmetric Michael Addition” C. G. Kokotos, D. Limnios, D. Triggidou, M. Trifonidou and G. Kokotos, Org. Biom. Chem., 2011, 9, 3386-3395.

 

14) “Prolinamides bearing Thiourea Groups as Catalysts for Asymmetric Aldol Reactions” S. Fotaras, C. G. Kokotos, E. Tsandi and G. Kokotos, Eur. J. Org. Chem., 2011, 1310-1317.

 

13) “Potent and Selective Fluoroketone Inhibitors of Group VIA Calcium-independent Phospholipase A2” G. Kokotos, Y.-H. Hsu, J. Burke, C. Baskakis, C. G. Kokotos, V. Magrioti and E. A. Dennis, J. Med. Chem., 2010, 53, 3602-3610.

 

12) “Interactions at the Bilayer Interface and Receptor Site Induced by the Novel Synthetic Pyrrolidinone Analog MMK3” C. Fotakis, S. Gega, E. Siapi, C. Potamitis, K. Viras, P. Moutevelis-Minakakis, C. G. Kokotos, S. Durdagi, S. Golic Grdadolnik, B. Sartori, M. Rappolt and T. Mavromoustakos, Biochim. Biophys. Acta Biomembranes, 2010, 1798, 422-432.

 

11) Bacillus subtilis Esterase (BS2) and its Double Mutant have Different Selectivity in the Removal of Carboxyl Protecting Groups” E. Barbayianni, C. G. Kokotos, S. Bartsch, C. Drakou, U. Bornscheuer and G. Kokotos, Adv. Synth. Catal., 2009, 351, 2325-2332.

 

10) “Primary Amine-thioureas based on tert-Butyl Esters of Natural Amino Acids as Organocatalysts for the Michael Reaction” C. G. Kokotos and G. Kokotos, Adv. Synth. Catal., 2009, 351, 1355-1362.

 

9) “Sulfonamides of Homoproline and Dipeptides as Organocatalysts for Michael and Aldol Reactions” E. Tsandi, C. G. Kokotos, S. Kousidou, V. Ragoussis and G. Kokotos, Tetrahedron, 2009, 65, 1444-1449.

 

8) “Synthesis of Medicinally Interesting Polyfluoro Ketones via Perfluoroalkyl Lithium Reagents” C. G. Kokotos, C. Baskakis and G. Kokotos, J. Org. Chem., 2008, 73, 8623-8626.

 

7) “Sulfur Ylide Mediated Three-component Aziridination and Epoxidation Reactions using Vinyl Sulfonium Salts” C. G. Kokotos, E. M. McGarrigle and V. K. Aggarwal, Synlett, 2008, 2191-2195, highlighted in Synfacts, 2008, 11, 1142.

 

6) “Aminals as Substrates for Sulfur Ylides: A Synthesis of Functionalised Aziridines and N-Heterocycles” C. G. Kokotos and V. K. Aggarwal, Org. Lett., 2007, 9, 2099-2102.

 

5) “A Practical Synthesis of a [2.2.1] Bicyclic Chiral Sulfide for Asymmetric Transformations” V. K. Aggarwal, G. Fang, C. G. Kokotos, J. Richardson and M. G. Unthank, Tetrahedron, 2006, 62, 11297-11303.

 

4) “Hemi-aminals as Substrates for Sulfur Ylides: Direct Asymmetric Syntheses of Functionalised Pyrrolidines and Piperidines” C. G. Kokotos and V. K. Aggarwal, Chem. Commun., 2006, 2156-2158.

 

3) “Synthesis, Binding Studies, and in vivo Biological Evaluation of Novel non-Peptide Antihypertensive Analogues” T. Mavromoustakos, P. Moutevelis-Minakakis, C. G. Kokotos, P. Kontogianni, A. Politi, P. Zoumpoulakis, J. Findlay, A. Cox, A. Balmforth, A. Zoga and E. Iliodromitis, Bioorg. Med. Chem., 2006, 14, 4353-4360.

 

2) “Systemic and Intrathecal Effects of a Novel Series of Phospholipase A2 Inhibitors on Hyperalgesia and Spinal PGE2 Release” T. L. Yaksh, G. Kokotos, C. I. Svensson, D. Stephens, C. G. Kokotos, B. Fitzsimmons, D. Hadjipavlou-Litina, X. Y. Hua and E. A. Dennis, J. Pharmacol. Exp. Ther., 2006, 316, 466-475.

 

1) “Synthesis and Activity of 2-Oxoamides containing Long Chain β-Amino Acids” V. Constantinou-Kokotou, A. Peristeraki, C. G. Kokotos, D. A. Six and E. A. Dennis, J. Peptide Sci., 2005, 11, 431-435.

 

 

 

119) “Organocatalytic activation of hydrogen peroxide: towards green and sustainable oxidations” E. T. Poursaitidis, P. L. Gkizis, I. Triandafillidi and C. G. Kokotos*, Chem. Sci., 2024, 14, doi: 10.1039/D3SC05618J. 

 

 

 

118) “Nitroarenes: The rediscovery of their photochemistry opens new avenues in organic synthesis” P. L. Gkizis, I. Triandafillidi, and C. G. Kokotos*, Chem, 2023, 9, 3401-3414.

 

 

117) “Organocatalytic Friedel-Crafts Arylation of Aldehydes with Indoles utilizing N-Heterocyclic Iod(az)olium Salts as the Halogen-Bonding Catalyst” E. M. Galathri, T. Kuczmera, B. J. Nachtsheim* and C. G. Kokotos*, Green Chem., 2024, 26, doi: 10.1039/D3GC03687A.

 

 

 

 

116) “UVA-Light Promoted Catalyst-Free Photochemical Aerobic Oxidation of Boronic Acids” P. L. Gkizis, C. T. Constantinou and C. G. Kokotos*, Eur. J. Org. Chem., 2023, e202300898.

 

 

 

115) “3H‐Phenothiazin‐3‐one: A New Photocatalyst for the Aerobic Photochemical Oxidation of Sulfides to Sulfoxides” C. K. Spyropoulou, E. Skolia, D. F. Flesariu, G. A. Zissimou, P. L. Gkizis, I. Triandafillidi, M. Athanasiou, G. Itskos, P. A. Koutentis and C. G. Kokotos*, Adv. Synth. Catal., 2023, 365, 2643-2650. (citations: 0) (IF: 5.4)

 

 

 

111) “Anthraquinone-catalyzed Photooxidation of Boronic Acids in a Bio-based Solvent (2-Me-THF)” P. L. Gkizis, S. K. Serviou, A. Balaskas, C. T. Constantinou, I. Triandafillidi, C. G. Kokotos*, Synlett, 2023


110) “Visible-Light-Promoted Reaction of N-Hydroxyphthalimide Esters with Vinyl Boronic Pinacol Ester” P. L. Gkizis, I. Triandafillidi, N. A. Stini, C. S. Batsika, C. G. Kokotos*, Eur. J. Org. Chem., 2023, 26







109) “A Photochemical Protocol for the Synthesis of Weinreb and Morpholine Amides from Carboxylic Acids” O. G. Mountanea, C. Mantzourani, M. G. Kokotou, C. G. Kokotos*, G. Kokotos, Eur. J. Org. Chem., 2023,





108) ''Sunlight- or UVA-Light-Mediated Synthesis of Hydroxamic Acids from Carboxylic Acids” Olga G. Mountanea, C. Mantzourani, Maroula G. Kokotou, C. G. Kokotos*, Eur.J. Org.Chem., 2023, 26,



107) “Photochemical upcycling of polystyrene plastics” E. Skolia, O. G. Mountanea and C. G. Kokotos*, Trends Chem., 2023, 5, 116-120.


106) “A General Metal-Free Protocol for the Visible-Light-Driven Protection of Carbonyls” L. Di Terlizzi, E. M. Galathri, S. Protti, C. G. Kokotos and M. Fagnoni*, ChemSusChem, 2023, 16, e202201998.



105) “Photochemical [2+2] Cycloaddition of Alkenes with Maleimides: Highlighting the Differences between N-Alkyl vs N-Aryl Maleimides” E. Skolia and C. G. Kokotos*, ACS Org Inorg Au, 2023, doi: 10.1021/acsorginorgau.2c00053.


104) “Light-accelerated “on-water” hydroacylation of dialkyl azodicarboxylates” N. A. Stini, E. T. Poursaitidis, N. F. Nikitas, M. Kartsinis, N. Spiliopoulou, P. Ananida-Dasenaki and C. G. Kokotos*, Org. Biomol. Chem., 2023, DOI: 10.1039/D2OB02204D.


103) “Friedel–Crafts arylation of aldehydes with indoles utilizing arylazo sulfones as the photoacid generator” E. M. Galathri, L. Di Terlizzi, M. Fagnoni, S. Protti and C. G. Kokotos*, Org. Biomol. Chem., 2023, 21, 365-369. (IF: 3.89)



102) “Cyrene: A Bio-based Solvent for the Mizoroki-Heck Reaction of Aryl Iodides” N. A. Stini, P. L. Gkizis and C. G. Kokotos*, Org. Biomol. Chem., 2023, 21, 351-358.


101) “Photochemical Aerobic Upcycling of Polystyrene Plastics to Commodity Chemicals” N. F. Nikitas and C. G. Kokotos*, ChemRxiv, 2022, doi: 10.26434/chemrxiv-2022-l8p90.


100) “Cyrene: a Bio-based Novel and Sustainable Solvent for Organic Synthesis” N. A. Stini, P. L. Gkizis and C. G. Kokotos*, Green Chem., 2022, 24, 6435-6449.



99) “Light-promoted Oxidation of Aldehydes to Carboxylic Acids under Aerobic and Photocatalyst-free Conditions” C. S. Batsika, C. Koutsilieris, G. S. Koutoulogenis, M. G. Kokotou, C. G. Kokotos* and G. Kokotos*, Green Chem., 2022, 24, 6224-6231.




98) “A Sustainable Photochemical Aerobic Sulfide Oxidation: Access to Sulforaphane and Modafinil” E. Skolia, P. L. Gkizis and C. G. Kokotos*, Org. Biomol. Chem., 2022, 20, 5836-5844.


97) “Organocatalytic Synthesis of Thiiranes from Alkenes” A. Tsoukaki, E. Skolia, I. Triandafillidi* and C. G. Kokotos*, Eur. J. Org. Chem., 2022, e202200463. Hot Topic Organocatalysis, Highlighted at ChemistryViews:


96) “Photochemical Aerobic Oxidation of Sulfides to Sulfoxides: The Crucial Role of Wavelength Irradiation” E. Skolia, P. L. Gkizis, N. F. Nikitas and C. G. Kokotos*, Green Chem, 2022, 24, 4108-4118.




95) “Aerobic Photocatalysis: Oxidation of Sulfides to Sulfoxides” E. Skolia, P. L. Gkizis and C. G. Kokotos*, ChemPlusChem, 2022, 87, doi: 10.1002/cplu.202200008.




94) “A Unified Mechanism for the PhCOCOOH-mediated Photochemical Reactions: Revisiting its Action and Comparison to Known Photoinitiators” N. Spiliopoulou, P. L. Gkizis, I. Triandafillidi, N. F. Nikitas, C. S. Batsika, A. Bisticha and C. G. Kokotos*, Chem. Eur. J., 2022, 28, doi: 10.1002/chem.202200023.




93) “Hexafluoroisopropanol-promoted or Brψnsted Acid-mediated Photochemical [2+2] Cycloadditions of Alkynes

92) “Photochemical C–H Acetalization of O-Heterocycles utilizing Phenylglyoxylic Acid as the Photoinitiator” G. S. Koutoulogenis, N. Spiliopoulou and C. G. Kokotos*, PhotoChem. PhotoBiol. Sci., 2022, doi: 10.1007/s43630-021-00126-7. Invited Contribution for Special Issue for Prof. Albini




91) “Aldehyde-Catalyzed Epoxidation of Unactivated Alkenes with Aqueous Hydrogen Peroxide” I. Triandafillidi, M. G. Kokotou, D. Lotter, C. Sparr* and C. G. Kokotos*, Chem. Sci., 2021, 12, 10191-10196. 



90) “Saturated Oxo Fatty Acids (SOFAs): A Previously Unrecognized Class of Endogenous Bioactive Lipids Exhibiting a Cell Growth Inhibitory Activity” C. S. Batsika, C. Mantzourani, D. Gkikas, M. G. Kokotou, O. G Mountanea, C. G. Kokotos P. K. Politis and G. Kokotos*, J. Med. Chem., 2021, 64, 5654-5666.



89) “Photochemical Activation of Aromatic Aldehydes: Synthesis of Amides, Hydroxamic Acids and Esters” N. F. Nikitas, M. K. Apostolopoulou, E. Skolia, A. Tsoukaki and C. G. Kokotos*, Chem. Eur. J., 2021, 27, 7915-7922.



88) “Thioxanthone: A Powerful Photocatalyst for Organic Reactions” N. F. Nikitas, P. L. Gkizis and C. G. Kokotos*, Org. Biomol. Chem., 2021, 19, 5237-5253.


87) “Organocatalytic, Organic Oxidant Promoted, Enamine C
H Oxidation/Cyclopropanation Reaction” Z. Džambaski, A. M. Bondžić, I. Triandafillidi, C. G. Kokotos and B. P. Bondžić*, Adv. Synth. Catal., 2021, 363, 4002–4008.



86) “Photochemical Metal-free Aerobic Oxidation of Thiols to Disulfides” N. Spiliopoulou and C. G. Kokotos*, Green Chem., 2021, 23, 546-551.



85) “Metal
free Photochemical Atom Transfer Radical Addition (ATRA) of BrCCl3 to Alkenes” N. F. Nikitas, E. Voutyritsa, P. L. Gkizis and C. G. Kokotos*, Eur. J. Org. Chem., 2021, 96-101. Invited Contribution for Special Issue: YourJOC Talents



84) “Photochemical Synthesis of Benzimidazoles from Diamines and Aldehydes” E. Skolia, M. K. Apostolopoulou, N. F. Nikitas and C. G. Kokotos*, Eur. J. Org. Chem., 2021, 422-428.



83) “Photochemical Reaction of N,N
Dimethylanilines with NSubstituted Maleimides Utilizing Benzaldehyde as the Photoinitiator” N. F. Nikitas, M. A. Theodoropoulou and C. G. Kokotos*, Eur. J. Org. Chem., 2021, 1168-1173. Invited Contribution for Special Issue: Hot Topic: Organocatalysis


82) “Phenylglyoxylic Acid: An Efficient Initiator for the Photochemical Hydrogen Atom Transfer (HAT) C
H Functionalization of Heterocycles” G. N. Papadopoulos, M. G. Kokotou, N. Spiliopoulou, N. F. Nikitas, E. Voutyritsa, D. I. Tzaras, N. Kaplaneris and C. G. Kokotos*, ChemSusChem, 2020, 13, 5934-5944.



81) “Photochemical Functionalization of Heterocycles with EBX Reagents; C
H Alkynylation versus Deconstructive Ring Cleavage” E. Voutyritsa, M. Garreau, M. G. Kokotou, I. Triandafillidi, J. Waser* and C. G. Kokotos*, Chem. Eur. J., 2020, 26, 14453-14460.



80) “Green Metal-Free Photochemical Hydroacylation of Unactivated Olefins” E. Voutyritsa and C. G. Kokotos*, Angew. Chem. Int. Ed., 2020, 59, 1735-1741.




79) “Photochemical Synthesis of Acetals utilizing Schreiner's Thiourea as the Catalyst” N. Spiliopoulou, N. F. Nikitas and C. G. Kokotos*, Green Chem., 2020, 22, 3539-3545.

78) “Photochemical oxidation of benzylic primary and secondary alcohols utilizing air as the oxidant” N. F. Nikitas, D. I. Tzaras, I. Triandafillidi and C. G. Kokotos*, Green Chem., 2020, 22, 471-477.



77) “Aldehydes as powerful initiators for photochemical transformations” M. A. Theodoropoulou, N. F. Nikitas and C. G. Kokotos*, Beilstein J. Org. Chem., 2020, 16, 833-857.



76) “Synthetic Approaches to Acyl Hydrazides and Their Use as Synthons in Organic Synthesis” N. Spiliopoulou, C. T. Constantinou, I. Triandafillidi* and C. G. Kokotos*, Synthesis, 2020, 22, 3219-3230.




75) “Recent advances in reactions promoted by amino acids and oligopeptides” I. Triandafillidi, E. Voutyritsa and C. G. Kokotos*, Phys. Sci. Rev., 2020, 5, doi.org/10.1515/psr-2018-0086.


74) “Photochemical Hydroacylation of Michael Acceptors Utilizing an Aldehyde as Photoinitiator” I. K. Sideri, E. Voutyritsa and C. G. Kokotos*, ChemSusChem, 2019, 12, 4194-4201.



73) “Synthesis of γ-Lactones Utilizing Ketoacids and Trimethylsulfoxonium Iodide” I. Triandafillidi, A. Savvidou and C. G. Kokotos*, Org. Lett., 2019, 21, 5533-5537.



72) “Synthesis of Benzofuran and Indole Derivatives Catalyzed by Palladium on Carbon” A. Savvidou, D. I. Tzaras, G. S. Koutoulogenis, A. Theodorou and C. G. Kokotos*, Eur. J. Org. Chem., 2019, 3890-3897.



71) “Photoorganocatalytic Synthesis of Acetals from Aldehydes” N. F. Nikitas, I. Triandafillidi and C. G. Kokotos*, Green Chem., 2019, 21, 669-674.


70) “Enantioselective Organocatalytic Enamine C-H Oxidation/Diels-Alder Reaction” Z. Dzambaski, D.-I. Tzaras, S. Lee, C. G. Kokotos and B. P. Bondzic*, Adv. Synth. Catal., 2019, 361, 1792-1797.



69) “Photocatalytic Atom Transfer Radical Addition to Olefins utilizing Novel Photocatalysts” E. Voutyritsa, I. Triandafillidi, N. V. Tzouras, N. F. Nikitas, E. K. Pefkianakis, G. C. Vougioukalakis and C. G. Kokotos*, Molecules, 2019, 24, 1644-1653.
68) “Photocatalytic Synthesis of γ-Lactones from Alkenes: High-Resolution Mass Spectrometry as a Tool to Study Photoredox Reactions” I. Triandafillidi, M. G. Kokotou and C. G. Kokotos*, Org. Lett., 2018, 20, 36-39.




67) “Organocatalytic Synthesis of Oxazolines and Dihydrooxazines from Allyl-Amides: Bypassing the Inherent Regioselectivity of the Cyclization” A. Theodorou, I. Triandafillidi and C. G. Kokotos*, Adv. Synth. Catal., 2018, 360, 951-957.



66) “Green Photo-Organocatalytic C
H Activation of Aldehydes: Selective Hydroacylation of Electron-Deficient Alkenes” G. N. Papadopoulos, E. Voutyritsa, N. Kaplaneris and C. G. Kokotos*, Chem. Eur. J., 2018, 24, 1726-1731.


65) “Expanding the Scope of Photocatalysis: Atom Transfer Radical Addition of Bromoacetonitrile to Aliphatic Olefins” E. Voutyritsa, I. Triandafillidi and C. G. Kokotos*, ChemCatChem, 2018, 10, 2466-2470.



64) “Photoorganocatalysis, Small Organic Molecules and Light in the Service of Organic Synthesis: the Awakening of a Sleeping Giant” I. K. Sideri, E. Voutyritsa and C. G. Kokotos*, Org. Biomol. Chem., 2018, 16, 4596-4614. Invited Review.



63) “Combining Οrganocatalysis with Photoorganocatalysis: Photocatalytic Hydroacylation of Asymmetric Organocatalytic Michael Addition Products” A. Schiza, N. Spiliopoulou, A. Shahu and C. G. Kokotos*, New J. Chem., 2018, 42, 18844-18849.
62) “Proline Dipeptides Containing Fluorine Moieties as Organocatalysts for the Asymmetric Aldol Reaction” A. Ahmetlli, N. Spiliopoulou, A. Magi-Oikonomopoulou, D.-T. Gerokonstantis, P. Moutevelis-Minakakis* and C. G. Kokotos*, Tetrahedron, 2018, 74, 5987-5995.



61) “Green Organocatalytic Oxidative Methods using Activated Ketones” I. Triandafillidi, D. I. Tzaras, and C. G. Kokotos*, ChemCatChem, 2018, 10, 2521-2535.




60) “Combining Prolinamides with 2-Pyrrolidinone: Novel Organocatalysts for the Asymmetric Aldol Reaction” I. Vlasserou, M. Sfetsa, D. T. Gerokonstantis, C. G. Kokotos* and P. Moutevelis-Minakakis*, Tetrahedron, 2018, 74, 2338-2349.



59) “Photoorganocatalytic Atom Transfer Radical Addition of Bromoacetonitrile to Aliphatic Olefins” E. Voutyritsa, N. F. Nikitas, M. K. Apostolopoulou, A. D. D. Gerogiannopoulou and C. G. Kokotos*, Synthesis, 2018, 50, 3395-3401. Invited Contribution for Special Issue: Photoredox Methods and their Strategic Applications in Synthesis



58) “Green Photoorganocatalytic Synthesis of Phenols from Arylboronic Acids” I. K. Sideri, E. Voutyritsa and C. G. Kokotos*, Synlett, 2018, 29, 1324-1328. Invited Contribution for Special Issue: 9th EuCheMS Organic Division Young Investigator Workshop


57) “Organocatalytic Synthesis of Lactones by the Oxidation of Alkenoic Acids” I. Triandafillidi, M. Raftopoulou, A. Savvidou, and C. G. Kokotos*, ChemCatChem, 2017, 9, 4120-4124.



56) “Photoorganocatalytic Synthesis of Lactones via a Selective C–H Activation–alkylation of Alcohols” N. Kaplaneris, A. Bisticha, G. N. Papadopoulos, D. Limnios and C. G. Kokotos*, Green Chem., 2017, 19, 4451-4456.

55) “Visible-Light-Mediated Catalytic Hydroacylation of Dialkyl Azodicarboxylates by Graphite Flakes” G. S. Koutoulogenis, M. G. Kokotou, E. Voutyritsa, D. Limnios, C. G. Kokotos*, Org Lett., 2017, 19, 1760-1763.



54) “Organocatalytic Oxidation of Substituted Anilines to Azoxybenzenes and Nitro Compounds: Mechanistic Studies Excluding the Involvement of a Dioxirane Intermediate” E. Voutyritsa, A. Theodorou, M. G. Kokotou and C. G. Kokotos*, Green Chem., 2017, 1291-1298. 2017 Green Chemistry Hot




53) “Green Organocatalytic Synthesis of Indolines and Pyrrolidines from Alkenes” A. Theodorou and C. G. Kokotos*, Adv. Synth. Catal., 2017, 359, 1577-1581.



52) “Green Organocatalytic Synthesis of Isoxazolines via a One-Pot Oxidation of Allyloximes” I. Triandafillidi and C. G. Kokotos*, Org. Lett., 2017, 19, 106-109.

51) “Photoinitiated Thiol-Ene “Click” Reaction: An Organocatalytic Alternative” D. Limnios and C. G. Kokotos*, Adv. Synth. Catal., 2017, 359, 323-328.


50) “Organocatalytic Synthesis of Polysubstituted Tetrahydrofurans from Alkenes” A. Theodorou and C. G. Kokotos*, Green Chem., 2017, 19, 670-674.


49) “Green Organocatalytic Dihydroxylation of Alkenes” A. Theodorou, I. Triandafillidi and C. G. Kokotos*, Eur. J. Org. Chem., 2017, 11, 1502-1509.




48) “Green Organocatalytic Synthesis of Dihydrobenzofurans by Oxidation-Cyclization of Allylphenols” I. Triandafillidi, I. K. Sideri, D. I. Tzaras, N. Spiliopoulou and C. G. Kokotos*, Synthesis, 2017, 49, 4254-4260. Invited Contribution for Special Issue: Modern Strategies in Cyclization


47) “Green Organocatalytic Oxidation of Sulfides to Sulfoxides and Sulfones” E. Voutyritsa, I. Triandafillidi and C. G. Kokotos*, Synthesis, 2017, 49, 917-924.



46) “Enantioselective Organocatalytic Synthesis of 2-Oxopiperazines from Aldehydes: Identification of the Elusive Epoxy Lactone Intermediate” N. Kaplaneris, C. Spyropoulos, M. G. Kokotou and C. G. Kokotos*, Org. Lett., 2016, 18, 5800-5803.



45) “One-pot Amide Bond Formation from Aldehydes and Amines via a Photoorganocatalytic Activation of Aldehydes” G. N. Papadopoulos and C. G. Kokotos*, J. Org. Chem., 2016, 81, 7023-7028.

44) “Photoorganocatalytic One-pot Synthesis of Hydroxamic Acids from Aldehydes” G. N. Papadopoulos and C. G. Kokotos*, Chem. Eur. J., 2016, 22, 6964-6967.



43) “Green Organocatalytic α-Hydroxylation of Ketones” E. Voutyritsa, A. Theodorou and C. G. Kokotos*, Org. Biomol. Chem., 2016, 14, 5708-5713. Invited Article for the Special Thematic issue “New Talent in Organic and Medicinal Chemistry”.



42) “(Thio)urea-mediated Synthesis of Functionalized Six-membered Rings with Multiple Chiral Centers” G. Koutoulogenis, N. Kaplaneris and C. G. Kokotos*, Beilstein J. Org. Chem., 2016, 12, 462-495. Invited Article for the Special issue “Multifunctional Organocatalysis”.




41) “4-Fluoro and 4-Hydroxy Pyrrolidine-thioxotetrahydropyrimidinones: Organocatalysts for Green Asymmetric Transformations in Brine” N. Kaplaneris, G. Koutoulogenis, M. Raftopoulou and C. G. Kokotos*, J. Org. Chem., 2015, 80, 5464-6473.


40) “tert-Butyl Esters of Peptides as Organocatalysts for the Asymmetric Aldol Reaction” A. Bisticha, I. Triandafillidi and C. G. Kokotos*, Tetrahedron: Asymmetry, 2015, 26, 102-108.



39) “One-pot Synthesis of O-Allylhydroxylamines through the Organocatalytic Oxidation of Tertiary Allylic Amines followed by a [2,3]-Meisenheimer Rearrangement” A. Theodorou, D. Limnios and C. G. Kokotos*, Chem. Eur. J., 2015, 21, 5238-5241.



38) “tert-Butyl Ester or Benzylamide of the Dipeptide Pro-Gly as Organocatalysts for the Asymmetric Aldol Reaction” I. Triandafillidi, A. Bisticha, E. Voutyritsa, G. Galiatsatou and C. G. Kokotos*, Tetrahedron, 2015, 71, 932-940



37) “Conjugating Proline Derivatives onto Multi-walled Carbon Nanotubes: Preparation, Characterization and Catalytic Activity in Water” D. D. Chronopoulos, C. G. Kokotos, M. Tsakos, N. Karousis, G. Kokotos and N. Tagmatarchis, Mat. Lett., 2015, 157, 212-214.


36) “Functionalized Multi-walled Carbon Nanotubes in an Aldol Reactions” D. D. Chronopoulos, C. G. Kokotos, N. Karousis, G. Kokotos* and N. Tagmatarchis*, Nanoscale, 2015, 7, 2750-2757.



35) “Organocatalytic Oxidation Reactions” D. Limnios and C. G. Kokotos*, Current Organocatalysis, 2015, 2, 171-190.



34) “Fullerene-proline Hybrids: Synthesis, Characterization and Organocatalytic Properties in Aldol Reactions” D. D. Chronopoulos, M. Tsakos, N. Karousis, C. G. Kokotos* and N. Tagmatarchis*, Mat. Lett., 2014, 137, 343-346.



33) “Photoorganocatalytic Hydroacylation of Dialkyl Azodicarboxylates by utilizing Activated Ketones as Photocatalysts” G. N. Papadopoulos, D. Limnios and C. G. Kokotos*, Chem. Eur. J., 2014, 20, 13811-13814.

32) “2,2,2-Trifluoroacetophenone: An Organocatalyst for an Environmentally Friendly Epoxidation of Alkenes” D. Limnios and C. G. Kokotos*, J. Org. Chem., 2014, 79, 4270-4276.

         
31) “One-pot Synthesis of Ureas from Boc-Protected Amines” C. Spyropoulos and C. G. Kokotos*, J. Org. Chem., 2014, 79, 4477-4483.


30) “2,2,2-Trifluoroacetophenone as an Organocatalyst for the Oxidation of Tertiary Amines and Azines to N-Oxides” D. Limnios and C. G. Kokotos*, Chem. Eur. J., 2014, 20, 559-563.


29) “tert-Butyl Esters of Tripeptides based on Pro-Phe as Organocatalysts for the Asymmetric Aldol Reaction in Aqueous or Organic Medium” A. Psarra, C. G. Kokotos* and P. Moutevelis-Minakakis*, Tetrahedron, 2014, 70, 608-615.


28) “Primary and Secondary Amine-(thio)ureas and Squaramides and their Applications in Asymmetric Organocatalysis” M. Tsakos and C. G. Kokotos*, Tetrahedron, 2013, 69, 10199-10222.


27) “Organocatalytic Oxidation of Organosilanes to Silanols” D. Limnios and C. G. Kokotos*, ACS Catalysis, 2013, 3, 2239-2243.


26) “β-tert-Butyl Aspartate as an Organocatalyst for the Asymmetric α-Amination of α,α-Disubstituted Aldehydes” A. Theodorou, G. N. Papadopoulos and C. G. Kokotos*, Tetrahedron, 2013, 69, 5438-5443.



25) “An Asymmetric Michael Addition of α,α-Disubstituted Aldehydes to Maleimides leading to a One-pot Enantioselective Synthesis of Lactones Catalyzed by Amino Acids” C. G. Kokotos*, Org. Lett., 2013, 15, 2406-2409.



24) “Microwave-Assisted Organocatalytic Cross-Aldol Condensation of Aldehydes” D. Limnios and C. G. Kokotos*, RSC Adv., 2013, 3, 4496-4499.

23) “Organocatalytic Asymmetric Domino Michael-Henry Reaction for the Synthesis of Substituted Bicyclo[3.2.1]octan-2-ones” M. Tsakos, M. R. J. Elsegood and C. G. Kokotos*, Chem. Commun., 2013, 49, 2219-2221.


22) “Novel Prolinamide-Ureas as Organocatalysts for the Asymmetric Aldol Reaction” P. Revelou, C. G. Kokotos* and P. Moutevelis-Minakakis*, Tetrahedron, 2012, 68, 8732-8738.

21) “Pyrrolidine-thioxotetrahydropyrimidinone as an Efficient Organocatalyst for the Enantioselective Michael Addition of Cyclic Ketones to Nitrodienes” M. Tsakos. M. Trifonidou and C. G. Kokotos*, Tetrahedron, 2012, 68, 8630-8635.

20) “A Tripeptide-like Prolinamide-Thiourea as an Aldol Reaction Catalyst” S. Fotaras, C. G. Kokotos and G. Kokotos, Org. Biomol. Chem., 2012, 10, 5613-5619. 

19) “Primary Amine-Thioureas with Improved Catalytic Properties for “Difficult” Michael Reactions. Efficient Organocatalytic Syntheses of (S)-, (R)-Baclofen and (S)-Phenibut” M. Tsakos, C. G. Kokotos and G. Kokotos, Adv. Synth. Catal., 2012, 354, 740-746.

18) “Enantioselective Organocatalytic α-Alkylation of Ketones Utilising SN-1 Type Reaction of Alcohols” M. Trifonidou and C. G. Kokotos*, Eur. J. Org. Chem., 2012, 1563-1568.

17) “Construction of Tertiary Alcohols Bearing Perfluoroalkyl Chains Catalyzed by Prolinamide-Thioureas” C. G. Kokotos*, J. Org. Chem., 2012, 77, 1131-1135.

16) “Organocatalytic “Difficult” Michael Reaction of Ketones with Nitrodienes Utilising Primary Amine-Thioureas Based on di-tert-Butyl Esters of Aspartic Acid” M. Tsakos and C. G. Kokotos*, Eur. J. Org. Chem., 2012, 576-580.

15) “Novel Pyrrolidine-thiohydantoins/thioxotetrahydropyrimidinones as Highly Effective Catalysts for the Asymmetric Michael Addition” C. G. Kokotos, D. Limnios, D. Triggidou, M. Trifonidou and G. Kokotos, Org. Biom. Chem., 2011, 9, 3386-3395.

14) “Prolinamides bearing Thiourea Groups as Catalysts for Asymmetric Aldol Reactions” S. Fotaras, C. G. Kokotos, E. Tsandi and G. Kokotos, Eur. J. Org. Chem., 2011, 1310-1317.

13) “Potent and Selective Fluoroketone Inhibitors of Group VIA Calcium-independent Phospholipase A2” G. Kokotos, Y.-H. Hsu, J. Burke, C. Baskakis, C. G. Kokotos, V. Magrioti and E. A. Dennis, J. Med. Chem., 2010, 53, 3602-3610.

12) “Interactions at the Bilayer Interface and Receptor Site Induced by the Novel Synthetic Pyrrolidinone Analog MMK3” C. Fotakis, S. Gega, E. Siapi, C. Potamitis, K. Viras, P. Moutevelis-Minakakis, C. G. Kokotos, S. Durdagi, S. Golic Grdadolnik, B. Sartori, M. Rappolt and T. Mavromoustakos, Biochim. Biophys. Acta Biomembranes, 2010, 1798, 422-432.

11) “Bacillus subtilis Esterase (BS2) and its Double Mutant have Different Selectivity in the Removal of Carboxyl Protecting Groups” E. Barbayianni, C. G. Kokotos, S. Bartsch, C. Drakou, U. Bornscheuer and G. Kokotos, Adv. Synth. Catal., 2009, 351, 2325-2332.

10) “Primary Amine-thioureas based on tert-Butyl Esters of Natural Amino Acids as Organocatalysts for the Michael Reaction” C. G. Kokotos and G. Kokotos, Adv. Synth. Catal., 2009, 351, 1355-1362.

9) “Sulfonamides of Homoproline and Dipeptides as Organocatalysts for Michael and Aldol Reactions” E. Tsandi, C. G. Kokotos, S. Kousidou, V. Ragoussis and G. Kokotos, Tetrahedron, 2009, 65, 1444-1449.

8) “Synthesis of Medicinally Interesting Polyfluoro Ketones via Perfluoroalkyl Lithium Reagents” C. G. Kokotos, C. Baskakis and G. Kokotos, J. Org. Chem., 2008, 73, 8623-8626.

7) “Sulfur Ylide Mediated Three-component Aziridination and Epoxidation Reactions using Vinyl Sulfonium Salts” C. G. Kokotos, E. M. McGarrigle and V. K. Aggarwal, Synlett, 2008, 2191-2195, highlighted in Synfacts, 2008, 11, 1142.

6) “Aminals as Substrates for Sulfur Ylides: A Synthesis of Functionalised Aziridines and N-Heterocycles” C. G. Kokotos and V. K. Aggarwal, Org. Lett., 2007, 9, 2099-2102.

5) “A Practical Synthesis of a [2.2.1] Bicyclic Chiral Sulfide for Asymmetric Transformations” V. K. Aggarwal, G. Fang, C. G. Kokotos, J. Richardson and M. G. Unthank, Tetrahedron, 2006, 62, 11297-11303.

4) “Hemi-aminals as Substrates for Sulfur Ylides: Direct Asymmetric Syntheses of Functionalised Pyrrolidines and Piperidines” C. G. Kokotos and V. K. Aggarwal, Chem. Commun., 2006, 2156-2158.

3) “Synthesis, Binding Studies, and in vivo Biological Evaluation of Novel non-Peptide Antihypertensive Analogues” T. Mavromoustakos, P. Moutevelis-Minakakis, C. G. Kokotos, P. Kontogianni, A. Politi, P. Zoumpoulakis, J. Findlay, A. Cox, A. Balmforth, A. Zoga and E. Iliodromitis, Bioorg. Med. Chem., 2006, 14, 4353-4360.

2) “Systemic and Intrathecal Effects of a Novel Series of Phospholipase A2 Inhibitors on Hyperalgesia and Spinal PGE2 Release” T. L. Yaksh, G. Kokotos, C. I. Svensson, D. Stephens, C. G. Kokotos, B. Fitzsimmons, D. Hadjipavlou-Litina, X. Y. Hua and E. A. Dennis, J. Pharmacol. Exp. Ther., 2006, 316, 466-475.

1) “Synthesis and Activity of 2-Oxoamides containing Long Chain β-Amino Acids” V. Constantinou-Kokotou, A. Peristeraki, C. G. Kokotos, D. A. Six and E. A. Dennis, J. Peptide Sci., 2005, 11, 431-435.