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Prokopios
MAGIATIS Assistant
Professor of the Pharmacognosy and
Natural Products Chemistry Department |
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- Bachelor in Pharmacy, - M.Sc. in
Pharmacognosy, - Ph.D in Pharmacognosy, - PostDoc,
Insitut Curie, Paris, France (2001) |
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Fields of interest -Isolation of compounds with pharmaceutical
and nutraceutical interest from natural sources. Search of new lead compounds
of plant and marine origin from Greek and -Natural products structure determination using
modern NMR techniques, Mass spectrometry and Molecular Modeling. -Design and synthesis of new molecules with
pharmacological interest (kinase inhibitors, neuroprotective agents,
antitumor, antibiotics, estrogen/antiestrogen) based on a natural product
core; structure-activity relationships, optimization of lead compounds. -Treatment of agricultural wastes for the large
scale production of high added value natural products -Essential oils, volatile, flavor and aroma constituents |
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Distinctions -
Egon Stahl Award (Silver). Top scientist in Europe under 40 years old for
2009 in the fields of Parmacognosy, analytical phytochemistry,
pharmaceutical biology and synthesis of natural products. Source: Society of
Medicinal Plants and Natural Product Research (GA) (Award
Lecture Geneva 17 August 2009) -
Award of American Society of Pharmacognosy (5th
Joint Meeting of ASP, GA, AFERP, PSE Amsterdam (1999) -1st medal of performance and morals. Source: U. of Athens (1994) -
Honorary diploma for special academic performance (1st
prize). Source: 7nth Panhellenic Pharmaceutical Congress. (1994) - Honor in panhellenic examination in mathematics. Source: Greek Mathematics Society. (1987)
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Important publications - GSK-3 selective inhibitors derived from Tyrian purple
indirubins Meijer, L.; Skaltsounis, A.L.; Magiatis, P.; Polychronopoulos, P.; Knockaert, M.; Leost, M.; Ryan, X.P.; Vonica, C.A.; Brivanlou, A.; Greengard, P et al. Chemistry and Biology 2003, 10, 1255-1266 - 7-bromo-indirubins induce caspase-independent cell death Ribas, J.; Bettayeb, K.; Ferandin, Y.; Knockaert, M.; Totzke, F.; Schδchtele, C.; Mester, J.;
Polychronopoulos, P.; Magiatis, P.; Skaltsounis, A.L.; Boix, J.; Meijer, L. Oncogene 2006, 25, 6304-6318. - In vitro and in
vivo activity of chios mastic gum extracts and constituents against Helicobacter
pylori Paraschos S., Magiatis P., Mitaku S., Petraki K., Kaliaropoulos
A., Maragoudakis P., Mentis A., Sgouras D., Skaltsounis A.-L. Antimicrobial
Agents Chemotherapy 2007, 51, 551-559 - Polyphenolic compounds from red grapes acutely
improve endothelial function in patients with coronary heart disease J. Lekakis, L. Rallidis, I. Andreadou, G. Vamvakou, G. Kazantzoglou, P. Magiatis, A. L. Skaltsounis, D. Kremastinos. European Journal of
Cardiovascular Prevention and Rehabilitation 2005, 12, 596-600. - "The olive constituent oleuropein exhibits anti-ischemic, antioxidative, and hypolipidemic
effects in anesthetized rabbits I. Andreadou, E.
Iliodromitis, E. Mikros, M. Constantinou, A. Agalias, P. Magiatis, A.
Skaltsounis, D. Kremastinos. J. Nutrition 2006, 136, 2213-2219 - Malassezia furfur isolated from seborrheic dermatitis skin lesions produces the AhR ligands malassezin and indole[3,2-b]carbazole Gaitanis, G.;
Magiatis, P.; Stathopoulou, K.; Velegraki, A.; Bassukas, I.; Alexopoulos, E.; Skaltsounis, A.L Journal of Investigative Dermatology 2008, 128, 1620-1625. |
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Contact Prokopios Magiatis Department of Pharmacognosy and Natural Products
Chemistry Faculty of Pharmacy University of Athens Panepistimioupolis Zografou 15 771 Athens, Greece Tel: ++30 10 727-4052, -4582 Fax: ++30 10
727-4594 E-mail: magiatis@pharm.uoa.gr |
