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Interaction of Stable Colloidal Nanoparticles and Cellular Membranes

Biotechnology Advances, 2014, 32, 679-692. DOI: 10.1016/j.biotechadv.2013.11.012

Nanoparticles and cellular membranes

Abstract

Due to their ultra-small size, inorganic nanoparticles (NPs) have distinct properties compared to their bulk form. The unique characteristics of NPs are broadly exploited in biomedical sciences to develop various methods of targeted drug delivery, novel biosensors, and new therapeutic pathways. However, relatively little is known about the negotiation of NPs with complex biological environments. Cell membranes (CMs) in eukaryotes have dynamic structures, which is a key property for cellular responses to NPs. In this review, we discuss the current knowledge of various interactions between advanced types of NPs and CMs.

For citation:
Mahmoudi, M.; Meng, J.; Xue, X.; Liang, X. J.; Rahman, M.; Pfeiffer, C.; Hartmann, R.; Gil, P. R.;
Pelaz, B.; Parak, W. J.; del Pino, P.; Carregal-Romero, S.; Kanaras, A. G.; Selvan, S. T.
"Interaction of Stable Colloidal Nanoparticles and Cellular Membranes"
Biotechnology Advances, 2014, 32, 679-692. DOI: 10.1016/j.biotechadv.2013.11.012

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