Publications
Table of Contents (TOC)
Gold Nanoparticles and Fluorescently-Labelled DNA as a Platform for Biological Sensing
Nanoscale, 2013, 5 (20), 9503-9510 DOI: 10.1039/c3nr03707j
Abstract
In the past decade, gold nanoparticle–nucleic acid conjugates have become increasingly important for biomedical applications. Fluorophores attached to nucleic acid-gold nanoparticle conjugates have opened up a new era of biological sensing. The most promising advancement in this field was the invention of so-called “nano-flare” systems. These systems are capable of detecting specific endocellular targets such as mRNAs, microRNAs, or small molecules in real time. In this minireview, we discuss the current progress in the field of DNA-nanoparticles as sensors, their properties, stability, cellular uptake, and cytotoxicity.
For citation:
Heuer-Jungemann, A.; Harimech, P.; Brown, T.; Kanaras,* A. G.
Gold Nanoparticles and Fluorescently-Labelled DNA as a Platform for Biological Sensing
Nanoscale, 2013, 5 (20), 9503-9510 DOI: 10.1039/c3nr03707j