Double stranded DNA immobilized on gold nanoparticles is amenable to enzymatic cleavage by a range of restriction endonucleases, and the efficiency of the cleavage can be quantified using fluorescence spectroscopy.
For citations:
Wang Z.; Kanaras A. G.; Bates A. D.; Cosstick R.; Brust M.
Enzymatic DNA Processing on Gold Nanoparticles
J. Mater. Chem., 2004, 14 (4), 578-580
DOI: 10.1039/B314328G