We discuss a hyperspectral darkfield microscopy technique capable of imaging single nanoparticles at biologically compatible (<0.5 W/cm2 ) illumination conditions. The microscope was tested on an array of lithographically produced gold nanorod antennas and on colloidal gold nanorods deposited on a glass substrate. As a test for in-vitro imaging capabilities, we studied the uptake of gold nanorods by DC2.4 dendritic cells
For citations:
Fairbairn, N.; Fernandes, R.; Carter, R.; Elliot, J. E.; Kanaras, A. G.; Muskens, O. L.
Single-nanoparticle detection and spectroscopy in cells using a hyperspectral darkfield imaging technique
Proc. SPIE 8595, Colloidal Nanocrystals for Biomedical Applications VIII, 2013, 859501 doi: 10.1117/12.981941