Publications
Table of Contents (TOC)
Investigating the stability of DNA-coated gold nanoparticles
Proc. SPIE, 10507, Colloidal Nanoparticles for Biomedical Applications XIII; 2018, 105070A doi:10.1117/12.2285833
Abstract
In this paper we investigate how the density of oligonucleotides around spherical 15 nm gold nanoparticles (AuNPs) influences their stability against degradation by DNase I. We show that a significant decrease in the number of oligonucleotides attached to the AuNP surface is directly correlated with an increase in the DNA degradation by DNase I. Our experimental observations suggest that a close packing of oligonucleotides into a 3d arrangement at the surface of AuNPs endows the probes with the necessary stability required for their use in intracellular applications.
For citations:
Kyriazi, M. E.; Kanaras,* A. G.
Investigating the stability of DNA-coated gold nanoparticles
Proc. SPIE, 10507, Colloidal Nanoparticles for Biomedical Applications XIII; 2018, 105070A doi:10.1117/12.2285833