Silver Nanoclusters with Broad Spectrum Antibacterial Properties

ACS Omega 2025, asap doi:10.1021/acsomega.5c00163

Abstract

Bacteria resistance to antibiotics is a significant threat to global health, and innovative strategies are needed to tackle bacterial infections. In this study, we used an in vitro bactericidal assay to demonstrate that small silver nanoclusters (AgNCs) coated with 5-mercapto-2-nitrobenzoic acid (MNBA) have bactericidal activity against a range of Gram-negative and Gram-positive ESKAPEE bacteria and bacteria belonging to the WHO Priority Pathogen List. Understanding the broad-spectrum antibacterial properties of MNBA-AgNCs highlights the importance of nanoparticle customization to further combat antimicrobial resistance.

For citation:
Cook, I. J.; Kyriazi, M. E.; Christodoulides,* M.; Kanaras,* A. G.
"Silver Nanoclusters with Broad Spectrum Antibacterial Properties"
ACS Omega 2025, asap doi:10.1021/acsomega.5c00163

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